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Recent reports that a young woman working in a Russian biolab became ill and died echo Annie Jacobsen’s new book, Biological War: A Scenario. How concerned should we be?
A few months ago, I ordered a pre-publication copy of Annie Jacobsen’s new non-fiction book, Biological War: A Scenario, which followed on from her excellent book, Nuclear War: A Scenario—not because I enjoy reading about existential risks, but because I’m an information seeker and feel that it’s important to stay informed. But when it arrived a few weeks later, in spite of having written an opinion piece about her nuclear book, entitled, “Why We Avoid Thinking About Nuclear War—and Why We Shouldn’t,” after seeing the frightening cover illustration of men in hazmat suits, I stashed it on the bookshelf of my study rather than reading it—for the same reasons I discussed in my earlier piece: I didn’t want to know!
But after the recent reports of a biolab accident in Russia, I retrieved it from the bookshelf and read it in two days.
The “scenario” in the book is that of a “biological weapons lab accident,” where a scientist working to modify pneumonic plague into a deadly biological weapon experiences remorse and tries to destroy it. But the small fire he lights causes an explosion that propels the Yersinia pestis bacteria (which causes the plague) into the atmosphere. In the process, he becomes infected with his weaponized pneumonic plague, although he doesn’t yet know it.
Although most of us cannot directly influence negotiations about strengthening the BWC, there are things that we can do to support such efforts and to lessen the increasingly grave dangers that confront us.
The next morning, he goes to an Orthodox church to confess where, by coughing in the midst of confession, he infects the priest, as well as the next person in line—a pre-med foreign exchange student, who is back in this small Russian town visiting family—before returning to the US shortly thereafter, where he is studying and doing volunteer work with homeless people. The student subsequently infects scores on Skid Row, who, in turn, infect the first responders who come to help them and, ultimately, the whole city of Los Angeles.
Following his confession, the scientist goes into the woods to shoot himself but collapses from the symptoms of plague. He is found by men on an international hunting trip, who administer mouth-to-mouth resuscitation and carry him back to their hunting lodge, where he is collected by officials. After dining together, using the same sauna and steam bath, and driving to the airport in the same van, seven of the hunters board flights to six of the world’s seven continents, while another goes off on a sea cruise—spreading pneumonic plague on their flights and sea voyage—and ultimately around the world.
In the real-world scenario, reported on October 2, Darya Shipilova, a 28-year old laboratory technician working in an “Anti-Plague Institute” in Irkutsk, Siberia died, according to Russian officials, of “a pneumonia of unknown etiology.” A Russian news agency reported that she had broken a test tube containing live bacteria of the pneumonic plague pathogen, leading to widespread speculation that she had, indeed, died of pneumonic plague.
These concerns were reinforced by reports that Russian health authorities imposed sweeping quarantine restrictions on the lab where she worked, the hospital where she died, and other nearby hospitals. Neighbors also reported that workers in protective suits and gas masks repeatedly disinfected the building where she lived, telling residents that it was “for cockroaches,” although the building has no cockroaches. More recently, Russia’s health agency asserted that the plague was not detected in follow-up tests of “thousands of people in the region.”
The overall opacity (a familiar playbook for crises in Russia) of Russian public health officials in responding to urgent requests for more information from the World Health Organization, the US, and other governments led to considerable disquiet around the world.
When asked if her death was related to a bioweapon, President Donald Trump responded, not very reassuringly, “We don’t think so.” He also acknowledged the similarities in how Chinese officials handled Covid-19 before it became a global pandemic: “China didn’t say much, and Russia is not saying much either.”
The 1925 Geneva Protocol banned the use of biological weapons, but not their development or possession. Although ratified by a number of countries in the 1920s and 30s, it wasn’t ratified by the US until 1975.
After 27 years of a US biological weapons program, President Richard Nixon unexpectedly announced on November 25, 1969 that the US would unilaterally end its offensive biological weapons program, stating, “The United States shall renounce the use of lethal biological agents and weapons, and all other methods of biological warfare… [and] confine its biological research to defensive measures such as immunization and safety measures.” Over the next years, US biological weapons stocks were destroyed with the process completed in May 1972.
Subsequently, the United Nations Conference on Disarmament negotiated “The Biological Weapons Convention” (BWC), the first multilateral treaty to ban an entire class of weapons of mass destruction. It was opened for signature on April 10, 1972 and signed by the US, Great Britain, and the Soviet Union the same day. It entered into force on March 26, 1975. Currently, it has 189 State Parties and four Signatory States, with only four States outside the Convention.
Because it was the first of its kind, however, the BWC lacked the important monitoring and verification procedures that were later included in the Chemical Weapons Convention. There are no mandatory verified declarations of biological facilities or activities; no inspections or site visits to verify compliance; no international organization to oversee implementation; and no penalties for non-compliance, although complaints can be made to the UN Security Council (which are subject to veto by any of the five Permanent Members). Only four staff are involved in its tiny Implementation Support Unit, compared with over 500 for the Chemical Weapons Convention.
In spite of the Soviet Union becoming a signatory to the BWC in 1972, the USSR continued to covertly develop and produce offensive biological weapons in what became the world’s largest and most sophisticated biological weapons program, with 40-50 biological research facilities scattered around the country, employing 65,000 people. The aim was to create “exotic biological weapons using techniques made possible by recombinant DNA.” Recombinant DNA, also called genetic engineering, involves joining the DNA from two entirely different species to make new pathogens.
Not detecting this vast biological weapons program was one of the biggest intelligence failures of the Cold War as it was totally unknown in the West until 1989, when a Soviet scientist, Vladimir Pasechnik, defected, shocking the British Intelligence Services and the CIA with details of the massive program and its deadly stockpiles. They learned that the Soviets had “genetically engineered a strain of Yersinia pestis to resist antibiotics” and had also stockpiled vast volumes of other deadly pathogens in the labs’ freezers, such as smallpox, anthrax, ebola, Marburg virus disease, and many others—all weaponized to kill populations in the most diabolical manner.
The terrifying extent of this biowarfare program was later confirmed by other defecting Soviet scientists, especially after the collapse of the Soviet Union in 1991. In January 1992, Boris Yeltsin admitted that he knew about the program and pledged to close down the institutes, retire their directors, and ask for international inspections. But the two generals he appointed to carry out this mission resisted his orders. In 1992, a Trilateral Agreement was signed by Russia with the United States and the United Kingdom “promising to end biological weapons programs and convert facilities to benevolent purposes, but compliance with the agreement—and the fate of the former Soviet bio-agents and facilities—is still mostly undocumented.”
The State Department’s 2025 compliance report states: “The United States assesses that Russia maintains an offensive biological warfare program and is in violation of its obligations under Article I and II of the BWC… Key military biological facilities associated with the Soviet offensive program remain, inaccessible and not transparent, nearly 30 years after Yeltsin’s decree.”
The latter part of Jacobsen’s book deals with the breakdown of law and order, as mass death and panic take hold and cause chaos. Ultimately, the president deploys the Insurrection Act, whereby military forces attempt to establish martial law for the first time in American history. Just as they are about to release the strategic national stockpiles of medicine, scientists at the US Army Medical Research Institute of Infectious Disease receive their first bacterial specimens (from the infected hunter who landed in Dallas and died in a local hospital). Microbiologists in biocontainment suits examine the specimens, and plague cultures are grown and used to test for antibiotic resistance in small animals. Simultaneously, microbiologists extract DNA from the specimen and feed it into a high-speed sequencing machine to get a genetic fingerprint of the pathogen.
What they discover is appalling—the organism has been bioengineered and “looks alarmingly like a 21st century version of something Russian scientists worked on during the Soviet-era secret biological weapons programs.” It is a combination of two pathogens, one concealed within another, referred to as a “bobby-trap bio-weapon,” whereby, after a person becomes infected with pneumonic plague and takes antibiotics as soon as possible under the assumption they will be cured, the antibiotics trigger the chimera weapon’s bobby-trap mechanism—in this fictional case, the Venezuelan equine encephalitis gene which has been covertly spliced into the Yersinia pestis genome to cause acute neurological symptoms and death. As a result, there is no cure.
The book is not meant to create unnecessary fear. It is meant to make clear what is now possible, and what is at stake. The tools to engineer life are advancing faster than the rules that govern them. This gap is where existential danger lives. The point is not panic; the point is pressure. To demand guardrails, oversight, and accountability before the science outruns our ability to control it. Before we set something irreversible in motion.
Although the real-life situation in Siberia will hopefully not turn out to be the same as in Annie Jacobsen’s book, it should cause us to take notice.
Serious attempts have been made in the past to strengthen the BWC but without success. An Ad Hoc Group labored from 1995 to 2001 to create a protocol where states would submit declarations of treaty-relevant facilities and activities to an international body that would conduct routine on-site visits, as well as challenge inspections of suspect facilities and activities. But the draft was rejected by the US under President George W. Bush, who argued that it could harm US national security. Nothing more happened for many years.
Another attempt is currently underway, although progress is slow. A Biological and Toxin Weapons Convention Working Group was established at the 2022 BWC Review Conference and has been working steadily over the last four years to come up with the text of draft recommendations before the 2027 BWC Review Conference. At their August meeting this year, 90.6% of the text had been agreed, although fundamental disagreements over verification frameworks, transfer controls, and funding remain—and tensions are high.
The chair of the Working Group has highlighted the urgency, arguing that the sudden convergence of artificial intelligence and biology is “creating new security challenges,” warning that a gap “may emerge between these rapidly advancing capabilities and our collective ability to understand their governance and prevent their misuse.”
Although most of us cannot directly influence negotiations about strengthening the BWC, there are things that we can do to support such efforts and to lessen the increasingly grave dangers that confront us.
We can be sure to vote in the upcoming midterms for Democratic candidates, who have been more likely to support regulatory controls in Congress, as well as multilaterally. We can support these candidates with financial contributions and by working on their campaigns to ensure that they get elected, since time is short. Once elected, we can strive to persuade them to urgently implement appropriate policies.
After all, who wants human extinction? Presumably, none of us—no matter how jaded we may have become.
We can educate ourselves about the threats by reading widely, including Jacobsen’s excellent books, as well as opinion pieces on the subject, such as ones I’ve written on AI and nuclear weapons. We can do online research to identify, join, financially support, and work with others in public advocacy organizations against threats that are of particular concern to us. We can attend protest rallies and discuss our concerns with friends, encouraging them to also become active, so that we can develop a large public constituency to combat these extreme dangers.
Just a couple of days ago, on October 11, The Lancet Commission on 21st Century Global Threats to Health highlighted 17 major threats to human health over the next 75 years, asserting that, “Malicious use of AI, including bioweapons, and nuclear conflict with nuclear famine [caused by nuclear winter] carry risks of extinction in the next 75 years.” There are so many existential dangers to confront that it can sometimes feel overwhelming and lead us to a state of helplessness when what we need, instead, is a pro-active approach that will foster resourcefulness.
By facing up to our natural tendency to avoid frightening information and by confronting our fears head-on, we can gain a true sense of self-efficacy and social responsibility. In this way, we can save those we love; ensure that future generations thrive; preserve the rich cultural heritage we have created; protect the magnificent array of other species on Earth; and safeguard our beautiful, one-of-a-kind planet—from all of these truly insane and, frankly, evil machinations—often designed by normal people, who have been seduced by competitive processes; rationales that “everyone is doing it”; lucrative remuneration; lapse of conscience; and bad ideas into creating conditions for the most dystopian futures imaginable.
As Gareth Evans, former Australian foreign minister, former president and CEO of the International Crisis Group, and co-chair of the Commission on Nuclear Proliferation and Disarmament has recently commented with regard to the nuclear threat, “It is up to those of us who passionately believe in both the possibility and necessity of a nuclear weapon free world, however disappointed and frustrated we may be right now, to get out there and continue to campaign our hearts out for it.” I suggest that we extend his call to action to all the existential threats we face. After all, who wants human extinction? Presumably, none of us—no matter how jaded we may have become. We must assume responsibility for the continuation of our kind and choose human survival.
"Detecting the virus that causes polio in wastewater heralds a real health disaster," Gaza's health ministry said.
Poliovirus has been detected in sewage samples at six locations in the Gaza Strip, the World Health Organization said on Friday, following announcements from both the Israel and Gaza health ministries.
Vaccine-derived poliovirus type 2 was found in samples taken on June 23 from sites in Khan Younis and Deir al-Balah.
Public health authorities expressed grave concerns about the findings, which, though no cases have yet been discovered, raise the possibility of an outbreak of polio, a highly infectious disease that often causes paralysis and can be fatal.
"Detecting the virus that causes polio in wastewater heralds a real health disaster and exposes thousands of residents to the risk of contracting polio," Gaza's health ministry said in a statement.
Tanya Haj-Hassan, a pediatric intensive care physician, told Al Jazeera the presence of the poliovirus was a "ticking time bomb," especially given the lack of ability to isolate and care for people who contract the disease.
Haj-Hassan warned that it would be “catastrophic" if the disease spread among healthcare workers, given that the medical system has already been "annihilated by direct targeting, by abductions of healthcare workers, by [the] killing of healthcare workers."
Dahlia Scheindlin, a Tel Aviv-based political analyst, called news of the presence poliovirus "absolutely shocking, stunning, [and] unthinkable" in a series of social media posts.
"The health crisis in Gaza has been catastrophic from the start," Scheindlin wrote, seemingly addressing Israelis. "If you're incapable of realizing that civilians should never have been in this situation, maybe the prospect of anyone getting polio, river to sea, where we are 'one epidemiological family,' will get through."
Yes, it's happened. Polio detected in #Gaza sewage. IDF wants all soliders vaccinated/boosted. Live btwn river & sea and scared? you should be. Know what wd work well? Stopping the war, immediate rehab of Gaza's health system & all civilian infrastructure 1/7 🧵
— Dahlia Scheindlin (@dahliasc) July 18, 2024
Conditions in Gaza have been ripe for an outbreak of infectious disease—the "perfect environment" for transmission, as WHO spokesperson Christian Lindmeier called it, citing "decimation of the health system, lack of security, access obstruction, constant population displacement, shortages of medical supplies, poor quality of water and weakened sanitation."
In late June, The Associated Press reported on the nightmarish situation in Deir al-Balah, one of the areas where the poliovirus has since been discovered:
Children in sandals trudge through water contaminated with sewage and scale growing mounds of garbage in Gaza's crowded tent camps for displaced families. People relieve themselves in burlap-covered pits, with nowhere nearby to wash their hands.
Polio, which can spread through contact with the stool of an infected person, has been eliminated from much of the world following the development of a vaccine in the early 1950s and a campaign by U.N. agencies that began in 1980. Still, it hasn't been eradicated globally, and there's been a resurgence in Afghanistan and Pakistan in recent years.
Gaza has been polio-free for 25 years and 95% of the population was vaccinated against the disease as of 2022, according to the WHO, though Haj-Hassan, the pediatrician, said that many Gazans, including newborns, have gone without vaccines or boosters for the last nine months.
The WHO said that it's working with other U.N. agencies and health authorities in Gaza to assess how much the poliovirus has spread and determine what measures may be needed, including a "prompt" vaccination campaign.
Combatting any infectious diseases will present challenges for Gaza's public healthcare system, which has been embattled and largely destroyed by Israeli forces. Only 16 out of the enclave's 36 hospitals are even partially functional, and only 45 of the 105 primary health care facilities are operational, according to the WHO.
The lack of medical care is part of a broader public health disaster, people on the ground in Gaza say.
"We're talking about a very grim medical reality," said Tareq Abu Azzoum, an Al Jazeera journalist reporting from Deir al-Balah, which faces severe overcrowding due to the roughly 700,000 displaced Gazans who have fled there.
Abu Azzoum cited Israeli military tactics as a reason for the dire conditions, arguing that the problems stem from attacks on "water wells, sanitation, and water waste treatment" and the blocking of "essential hygiene supplies."
"Eventually we will see more people dying from disease than from bombardment if we are not able to put back together this health system," said a spokesperson for the global health agency.
With the brief "humanitarian pause" between Israel and Hamas so far failing to result in the delivery of sufficient aid in Gaza, United Nations officials on Tuesday warned that the spread of disease could soon begin killing more Palestinian people than Israel's bombs and raids.
Humanitarian groups have warned for weeks that Israel's total blockade of Gaza—cutting off deliveries of fuel, water, food, and electricity access—quickly fueled outbreaks of gastrointestinal illnesses as sanitation and water treatment services ground to a halt.
The World Health Organization (WHO) has now recorded more than 44,000 cases of diarrhea and 70,000 acute respiratory infections in Gaza since Israel began its latest bombardment of the enclave on October 7, with cases of gastrointestinal illness for those aged five and older rising to more than 100 times the normal level earlier this month.
"Everybody everywhere has dire health needs now because they are starving, because they lack clean water and they're crowded together," said Margaret Harris, a spokesperson for WHO, at a briefing in Geneva on Tuesday. "Basically, if you're sick, if your child has diarrhea, if you've got a respiratory infection, you're not going to get any [help]."
"Eventually we will see more people dying from disease than from bombardment if we are not able to put back together this health system," she added.
On social media, WHO reiterated its call for a permanent negotiated cease-fire and sustained aid access in Gaza to allow health officials to rebuild the decimated medical system.
Out of 36 hospitals in Gaza, about 26—or three-quarters—have entirely shut down due to damage from bombings and an inability to provide care to patients. Without fuel shipments and reliable electricity, doctors have been unable to run machinery needed to properly sterilize medical equipment, among other necessities.
Although the current truce has been in place for four days and was extended by two days on Tuesday, the Palestinian Ministry of Health reported that no fuel has arrived in northern Gaza for hospitals to run generators.
One doctor from al-Shifa Hospital, which was raided by the Israel Defense Forces (IDF) earlier this month, told the United Nations Children's Fund (UNICEF) that primary threats to children's safety were previously "very much from the air and now very much on the ground," as gastrointestinal and respiratory infections continue spreading.
"He was terrified as a medical professional in terms of the disease outbreak that is that is lurking here and how that will devastate children whose immune systems and lack of food…is making them perilously weak," UNICEF spokesperson James Elder said Tuesday.
At hospitals throughout Gaza, Elder said in a video briefing, "I met a lot of parents... They know exactly what their children need. They don't have access to safe water and it's crippling them."
Since last month, United Nations agencies and groups including Oxfam have warned that, cut off from access to clean water, Palestinians face an even more dire public health threat than the diseases that are already spreading: a potential cholera outbreak like the one that killed at least 97 people in 2022 in Syria and Lebanon.
"It's conceivable that the bacterium has been brought in and the conditions are now ripe for its spread," Richard Brennan, regional emergency director for WHO, told Al Jazeera in October.
The Palestine Red Crescent Society (PRCS) told the BBC Tuesday that about 200 aid trucks per day have been allowed into Gaza since the humanitarian pause began last week—an improvement over the roughly 45 trucks that entered the enclave each day before the truce, but only half the amount that brought aid to Gaza's 2.3 million residents daily before October 7.
"The situation has become more than dire and this aid is urgently and critically needed," PRCS spokesperson Nebal Farsakh told the BBC.
Amnesty International warned that Palestinian civil society groups are struggling to serve injured, ill, displaced, and traumatized residents as a number of European countries and the European Commission have suspended or restricted aid funding due to "unfounded allegations that funding has been diverted to 'terrorist organizations' or used for 'incitement to hatred and violence'."
The European Commission introduced "anti-incitement" clauses in all new contracts with Palestinian NGOs, subjecting them to third-party monitoring, even as it announced on November 21 that "no evidence has been found to date that money has been diverted for unintended purposes."
"Restricting the funding of Palestinian organizations only is discriminatory and would silence them by hampering their vital work and would further deprive victims of any prospect of protection," said Eve Geddie, director of Amnesty International's European Institutions Office.
"The credibility of European states who claim to champion human rights has already been already weakened by their failure to call for a cease-fire and by continuing to arm Israel as it kills thousands of Palestinians with impunity," added Geddie. "These discriminatory funding restrictions are damaging their credibility even further."
"Further expansion of fossil fuels is reckless and the data clearly shows that it threatens the health and well-being of every person," one report author said.
Heat-related deaths could rise by 370% if policymakers and energy executives allow temperatures to rise by 2°C above preindustrial levels by the end of the century, a new Lancet study found.
The Lancet Countdown on Health and Climate Change on Tuesday released its eighth annual report tracking the impact of the climate crisis on global health. It is the first to offer projections for the future. In particular, the report authors emphasized the need to phase out fossil fuels that are baking the planet, putting human health and the Earth's systems that sustain it at risk.
"The diagnosis in this report is very clear," Dr. Renee Salas, one of the 114 scientists behind the report who also works in emergency care at Massachusetts General Hospital and Harvard Medical School, told The New York Times. "Further expansion of fossil fuels is reckless and the data clearly shows that it threatens the health and well-being of every person."
The report first describes how the climate crisis is currently impacting health. 2023 saw the highest temperatures in more than 100,000 years, and this has exposed more people to dangerous heat, including the most vulnerable. Infants younger than 1 and adults older than 65 were exposed to double the heatwave days that they were between 1986 and 2005. What's more, heat-related deaths for those over 65 have climbed by 85% compared with 1990 through 2000.
In the U.S. alone, heat-related deaths for those over 65 increased by 88% from 2018 to 2022 compared with 2000 to 2004, and approximately 23,200 elderly adults died of heat exposure last year.
"These numbers remind me of the elderly patients I see in my own hospital with heatstroke," Salas told the Times.
"This is an industry that is actually killing people in large numbers and making them ill in even larger numbers."
Yet as stark as the U.S. numbers are, the report also points to growing inequalities between health outcomes in richer and poorer nations.
"We're facing a crisis on top of a crisis," Georgiana Gordon-Strachan, who directs The Lancet Countdown Regional Center for Small Island Developing States, told Euronews.
"People living in poorer countries, who are often least responsible for greenhouse gas emissions, are bearing the brunt of the health impacts, but are least able to access funding and technical capacity to adapt to the deadly storms, rising seas, and crop-withering droughts worsened by global heating," Gordon-Strachan said.
The report calls out the fossil fuel industry in particular, and says that the world is moving in the wrong direction in weening itself off of oil, gas, and coal.
"In 2022, The Lancet Countdown warned that people's health is at the mercy of fossil fuels and stressed the transformative opportunity of jointly tackling the concurrent climate change, energy, cost-of-living, and health crises for human health and well-being," the report authors said. "This year's report finds few signs of such progress."
For example, the authors noted that the early 2023 plans of the world's top 20 fossil fuel companies would overshoot the Paris agreement goals by 173% by 2040.
"All our indicators on the fossil fuel industry are extremely relevant because this is an industry that is actually killing people in large numbers and making them ill in even larger numbers," report co-author Paul Ekins, a University College of London economist, told The Associated Press.
If this level of inaction continues, the report's current indicators "could be just an early symptom of a very dangerous future unless we tackle climate change urgently," Lancet Countdown executive director Marina Romanello told AP .
If temperatures rise to 2°C above preindustrial levels by 2100, every health hazard tracked by the report will increase, Axios reported.
In this case, heat-related deaths would rise by 370% for people over 65 by mid-century and 683% by the last two decades of the century. If world leaders don't do anything to either prevent or adapt to climate change, those numbers would rise to 433% and 1,537% respectively. In the 2°C scenario, labor loss due to heat would rise by 50% by mid-century and heatwaves could push 524.9 million more people into food insecurity.
The risk of infectious diseases would also increase, with the ideal coastal conditions for the Vibrio pathogen increasing by 17% to 25% and the chance of catching dengue increasing by 36% to 37%.
However, the report said it was not too late to take action. Rapidly phasing out fossil fuels would both reduce climate risks and prevent many of the 1.9 million deaths every year due to air pollution from the burning of dirty fuels.
"There is still room for hope," Romanello told Euronoews, adding that the planned focus on health at the upcoming U.N. Climate Change Conference, or COP28, presented "the opportunity of our lifetime."
"If climate negotiations drive an equitable and rapid phaseout of fossil fuels, accelerate mitigation, and support adaptation efforts for health, the ambitions of the Paris agreement to limit global heating to 1.5°C are still achievable, and a prosperous healthy future lies within reach," Romanello said.
"The humanitarian suffering in Gaza has already reached catastrophic levels, and it's set to get worse unless something changes immediately," said one human rights official.
The infectious disease outbreaks that doctors on the ground, public health officials, and humanitarian groups have been warning about for weeks in Gaza appear to be in full force, the World Health Organization said Thursday as it reiterated its call for a cease-fire to save lives.
The global public health organization said authorities have reported a surge in cases of diarrhea, with more than half of those affected children under the age of 5, as Israel's decision to cut off fuel access in the blockaded enclave has shut down water desalination plants and disrupted waste collection. The circumstances have created "an environment conducive to the rapid and widespread proliferation of insects, rodents that can carry and transit diseases."
By Thursday, said the United Nations Office for the Coordination of Humanitarian Affairs, all of Gaza's 120 municipal water wells were expected to be depleted.
Health officials in the blockaded enclave, where nearly 11,000 civilians have now been killed, are also reporting nearly 9,000 cases of scabies and lice; 12,600 cases of skin rashes; more than 1,000 reports of chickenpox; and nearly 55,000 cases of upper respiratory infections as roughly 1.5 million displaced people crowd into hospitals, churches, schools, and shelters in search of safety from Israel's relentless bombardment.
The International Rescue Committee (IRC) warned that those disease outbreaks could soon give way to the spread of more deadly illnesses like cholera and typhoid due to 95% of residents' forced reliance on unsanitary water in the past month.
"The humanitarian suffering in Gaza has already reached catastrophic levels, and it's set to get worse unless something changes immediately," said Bob Kitchen, vice president of emergencies for IRC. "While the overwhelming driver of mortality remains the ongoing violence and destruction, a humanitarian ceasefire now would also serve to help aid agencies get ahead of a looming public health crisis within an already vast humanitarian crisis... The conditions are ripe for the spread of communicable and waterborne diseases—diseases that adversely affect children and lead to preventable deaths."
Al Jazeera reported earlier this month that experts have surmised Israel is intentionally leaving Palestinians in Gaza with a lack of safe drinking water, using "water access as a weapon of war" and intensifying the humanitarian catastrophe.
In overcrowded shelters run by the United Nations Relief and Works Agency, WHO said, an average of 160 people are sharing one toilet and there is only one shower for every 700 people, compounding the unsanitary conditions and raising the risk of disease outbreaks.
With aid convoys largely blocked at the Rafah crossing between Gaza and Egypt, cleaning supplies as well as medicines have no way of getting to hospitals and shelters, and water supplies that humanitarian groups have managed to get through the crossing are only 4% of what is needed.
Medical workers also don't have sufficient personal protective equipment, making it more likely that they will acquire and transmit infections to the patients they are desperately trying to care for.
The impending colder weather is raising alarm over the potential for worsening malnutrition and food shortages, particularly for more than 50,000 pregnant people and about 337,000 children under the age of 5 in Gaza.
Kitchen said groups including the IRC are working to scale up their infection control programs as quickly as they can but warned that their efforts will remain severely obstructed as long as powerful countries including the United States refuse to support calls for a cease-fire.
"Without a meaningful humanitarian cease-fire to allow the free flow of aid, the suffering of innocent Palestinian civilians will continue," said Kitchen. "Immediate and sustained diplomatic intervention is urgently needed to enable a humanitarian cease-fire, which would pave the way for addressing these pressing humanitarian and protection needs and halt the health catastrophe that will lead to more deaths, particularly among children."
WHO also reiterated its demand for "the unconditional release of all hostages [by Hamas] and a humanitarian cease-fire to prevent further death and suffering."
At the end of October 2015, the Brazilian state of Pernambuco, located in the northeast of the country, started reporting a dramatic increase in the number of babies born with microcephaly, a condition characterized by a shrunken head and brain. The cases in Pernambuco were soon followed by similar ones in the nearby states of Bahia and Paraiba.
The cases of microcephaly seemed to be connected to an outbreak of the Zika virus, first recognized in Uganda in the 1940s. Zika is transmitted by Aedes aegypti, a species of mosquito that thrives in stagnant water pools. In the same way as malaria, dengue, and Chikungunya, the Zika virus infection results in similar symptoms: fever, joint pain, and rashes.
Thus, ominously, parallel to the increased number of pregnant women infected with the Zika virus there was an increase of microcephaly cases in their children. Because CT scans of those babies' brains showed signs of calcification usually associated with an infectious disease rather than a genetic abnormality, many experts thought that their microcephaly was caused by the Zika virus.
Also, while in 2014 there were 150 reported cases of microcephaly across all of Brazil, 3,893 cases of microcephaly were reported in 2015, with Pernambuco accounting for almost a third of the total number of cases. It seemed clear that the Zika virus was causing the babies' microcephaly.
However, Dr. Margaret Chan, Director-General of the World Health Organization (WHO) suggested caution. "Although a causal link between Zika infection in pregnancy and microcephaly has not, and I must emphasize, has not been established, the circumstantial evidence is suggestive and extremely worrisome," she said. Dr. Chan's opinion was echoed by Dr. Patricia Pestana Garcez, a neurodevelopment expert who studies microcephaly at the Federal University of Rio de Janeiro in Brazil who said, "There is no direct evidence that the virus causes microcephaly." However, she added that circumstantial evidence was strong enough to advise everybody not to take chances.
At the same time that the role of the Zika virus in the production of microcephaly in children was being studied, some environmental activists called attention to the role of pesticides as the possible cause of this abnormality in children.
Many experts and environmental activists alerted on how some agricultural chemicals--such as paraquat, classified as "highly poisonous" by U.S. regulators--which have been banned or phased out in leading industrialized nations, continue being extensively used in many developing countries, notably Brazil. They are used primarily in Brazil's northeast, where almost a third of cases of microcephaly have occurred so far.
In the last few years, Brazil has become one of the top exporters of orange juice, sugar, coffee, beef, poultry and soybeans. Brazil's massive production of those items is probably due, in part, to the extensive use of pesticides, many of them highly toxic to humans.
According to the World Health Organization (WHO), at the global level, there are over three million cases of pesticide poisoning each year and more than 220,000 deaths, mostly in developing countries.
Exposure to some pesticides can cause a wide range of health problems such as memory loss, loss of coordination, behavioral effects and reduced motor skills. In addition, they may cause asthma, allergies, cancer, hormone disruption, and problems with reproduction and fetal development, such as microcephaly. Children are at greater risk of pesticide exposure because of their small size and their immune system is not fully developed.
Given these toxic effects of pesticides and that they are more heavily used in Brazil's north-east region, it is not unreasonable to think that, at least in some cases, microcephaly may be due to excessive use of toxic pesticides and that these effects have been unmasked by the Zika virus infection. It is also possible to think that microcephaly in children may have a multi-causal origin.
This situation poses the need to urgently investigate more thoroughly the effects of both the Zika virus and pesticides in causing microcephaly in children, and for the public health authorities of the countries most threatened by this virus to coordinate actions for the more effective control of the epidemic.
A new report from the Obama administration comparing two future scenarios--one with significant global action on climate change, and the other without--finds that the U.S. could save "tens of thousands of American lives, and hundreds of billions of dollars" annually by reducing global greenhouse gas emissions.
The analysis released Tuesday by the Environmental Protection Agency (EPA) quantifies "the vast economic, health, and environmental benefits that reducing global carbon pollution will have on the United States, reinforcing the need to act with a sense of urgency."
For example, Climate Change in the United States: Benefits of Global Action finds that lowering greenhouse gas emissions would have "a substantial effect on reducing the incidence of extreme temperature and precipitation events by the end of the century, as well as the impacts to humans and the environment associated with these extreme events." In fact, by 2100 such mitigation would help avoid 12,000 deaths annually associated with extreme temperatures in 49 U.S. cities, according to the EPA.
The benefits of global action--of the sort to be discussed at the COP21 climate conference in December--are wide-ranging, the study declares. Tackling global warming could help the U.S. save up to $7 billion by 2100 in road maintenance costs, 230,000-360,000 acres of cold-water fish habitat across the country, and up to $34 billion in power system costs. And taking action on climate change would have "significant public health benefits in the U.S.," such as avoiding tens of thousands of premature deaths, which translate into savings of $930 billion by 2100.
While it focuses on health and economic benefits for the U.S., the EPA's peer-reviewed report underscores that "[s]lowing and preventing human-induced climate change requires global-scale action; the U.S. must do its part but cannot act alone."
Not acting, meanwhile, would have specific, negative regional impacts. According to the White House, "without action on climate change, California is projected to face increasing risk of drought, the Rocky Mountain region will see significant increases in wildfires, and the mid-Atlantic and Southeast are projected to experience infrastructure damage from extreme temperatures, heavy rainfall, sea level rise, and storm surge."
Such findings echo those that comprise an ever-growing body of research. This week, a new paper was published in Nature Climate Change. The authors wrote: "The climate is changing: we have a new normal. The environment in which all weather events occur is not what it used to be. All storms, without exception, are different. Even if most of them look just like the ones we used to have, they are not the same."
A new report in The Lancet declares that the negative impacts of human-caused global warming have put at risk some of the world's most impressive health gains over the last half-century while exacerbating infectious disease patterns, air pollution, food insecurity and malnutrition, involuntary migration, displacement, and violent conflict.
In response to the EPA's report, Sierra Club executive director Michael Brune noted: "This study amplifies facts that have been clear for a while: cutting carbon pollution and growing clean energy will prevent hundreds of thousands of premature deaths, save hundreds of billions of dollars in damages from sea-level rise and extreme weather, and save consumers billions on their electric bills."
Watch the EPA's video for an introduction to the analysis: